събота, 26 януари 2013 г.
HTRA1
Serine protease HTRA1 is an enzyme that in humans is encoded by the HTRA1 gene.[1][2] The HTRA1 protein is composed of four distinctprotein domains. They are from amino-terminus to carboxyl-terminus an Insulin-like growth factor binding domain, a kazal domain, a trypsin-like peptidase domain and a PDZ domain.
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth
Етикети:
Biology,
C-terminus,
health,
HTRA1,
Macular degeneration,
PDZ domain,
Protease,
Protein,
Science and IT
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